Tier 0 · open
syngas -> medium-chain fatty acids
CONSORTIUM (additive)
corpus v0.3.0 · hash 3574ed92836e…
Model licensing
Every model in this run is openly redistributable (CC-BY). You may reuse them, including commercially, with attribution to each source. Nothing here needs to be obtained elsewhere.
Provenanced sample report (Syntropa discovery, role-aware Stage-1). Corpus v0.3.0 (15717 models, fingerprint 3574ed92836e) · tools v0.1.0 (git 38fbc04, code 7965284a0cdb) · env py3.13.13 win32 swiglpk5.0.13+osqp1.1.3+highspy1.15.1+pyscipopt6.2.1+optlang1.9.1 (deps fec80ac6eed5). Feed={'co': 20, 'hydrogen': 20} target=hxa mode=produce. Report id 9096e1ec191f (content-addressed to config + EXACT corpus + EXACT tools -> reproducible/auditable). Honest-by-construction: read the caveats.
Verdict: CONSORTIUM (additive)
a multi-member consortium achieves the target; emergence not established.
Super-additivity + honest scope
- Best SINGLE organism reaches 0.534; best CONSORTIUM reaches 3.054 (~5.7x) -- a real multi-member effect.
- The 3867 feedstock-dependent candidates are COMBINATIONS over a diverse front-end core and largely SHARE the finisher(s) ['embl_endozoicomonas_elysicola_dsm_22380', 'embl_halomonas_subterranea_cgmcc_1_6495'] -- they are variations on a small number of core relays, NOT 3867 independent discoveries. The biological finding is the finisher + its best partners, not the raw count.
Ranked feedstock-dependent candidates (top 10 of 3867)
| rank | n | production | emergence | members |
|---|---|---|---|---|
| 1 | 2 | 3.054 | additive | embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_sporobacter_termitidis_dsm_10068 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 2 | 2 | 3.015 | additive | embl_desulfosporosinus_youngiae_dsm_17734 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 3 | 2 | 3.007 | additive | embl_calderihabitans_maritimus_kkc1 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_endozoicomonas_elysicola_dsm_22380 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 4 | 2 | 3.004 | additive | embl_clostridium_aceticum_dsm_1496 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 5 | 2 | 3.003 | additive | embl_clostridium_carboxidivorans_p7 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 6 | 2 | 2.995 | additive | cme_gcf000382125 (CarveMe 1.6.6 reconstruction from NCBI RefSeq proteome/draft) + embl_endozoicomonas_elysicola_dsm_22380 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 7 | 2 | 2.986 | additive | embl_clostridium_formicaceticum_atcc_27076 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 8 | 2 | 2.967 | additive | embl_blautia_schinkii_dsm_10518 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 9 | 2 | 2.967 | additive | embl_acetitomaculum_ruminis_dsm_5522 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_halomonas_subterranea_cgmcc_1_6495 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
| 10 | 2 | 2.952 | additive | embl_clostridium_dakarense_ff1 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) + embl_endozoicomonas_elysicola_dsm_22380 (embl_gems (CarveMe RefSeq, Machado 2018)/draft) |
Attribution
Every model above is credited by id + source. Model authors: your reconstruction appears in this result. (Impact-ledger stamping = flywheel, pending.)
Caveats (disclosed up front)
- FBA proves a route is stoichiometrically POSSIBLE, not that a living cell will do it.
- Every consortium here is a HYPOTHESIS until cultured; nothing is wet-lab validated.
- Feedstock-dependence is the anti-medium-artifact control: withdraw the feed and the product must collapse (a NOT-feedstock-dependent result is flagged SUSPECT, not a discovery).
- The ranking score is a documented heuristic for human review, not a truth or biology claim.
- Stage-1 selects finisher x diverse front-ends; multi-finisher relays are out of scope. Stage-2 expansion of winners is pending -- these are PRELIMINARY until it runs.