Syntropa

Open science · consortium discovery

Find the community that closes the loop

Most useful metabolic routes are not one organism's job. Syntropa harmonizes thousands of genome-scale models into one queryable corpus, then searches it for consortia — communities whose members feed each other to reach a product none of them can make alone.

What you can do here

Browse the atlas

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What the corpus contains and — just as importantly — what it cannot express: source mix, phyla, oxygen niche, biosafety tier, and per-source licensing.

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Read discovery reports

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Worked examples with the full funnel: candidate consortia, cross-feeding, the flux-balance verdict, the thermodynamic gate, and every drop reason.

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Get the data

open · cite it

The corpus is a versioned, content-hashed dataset: cite it today by version and content hash, with a Zenodo DOI to follow, so a result can be reproduced against the exact corpus that produced it.

Data & licensing →

Run a search on your target

by request

Discovery runs are compute-heavy, so they are handled as requests rather than self-serve for now. Tell us the conversion you care about.

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How it stays honest

Every quantitative claim is computed, not asserted: flux balance for feasibility, a thermodynamic gate for free-energy sanity, and mass/charge conservation as the real filter. When a gate cannot decide, it says unknown rather than guessing.

And the limits are published with the results: flux balance proves stoichiometric possibility, not biological reality. Nothing here has been cultured yet. Every candidate is a hypothesis — which is precisely why we publish what is missing, so someone can go and test it.