lignin -> cis,cis-muconate -> adipic

Provenanced sample report (Syntropa discovery, role-aware Stage-1). Corpus v0.3.0 (15717 models, fingerprint 3574ed92836e) · tools v0.1.0 (git 38fbc04, code 7965284a0cdb) · env py3.13.13 win32 swiglpk5.0.13+osqp1.1.3+highspy1.15.1+pyscipopt6.2.1+optlang1.9.1 (deps fec80ac6eed5). Feed=None target=None mode=produce. Report id 8a337edc49a8 (content-addressed to config + EXACT corpus + EXACT tools -> reproducible/auditable). Honest-by-construction: read the caveats.

Verdict: NOT-EXPRESSIBLE

MEASURED: feedstock present (bz 6679, 4hbz 2930) but the TARGET is absent -- 0 models carry a muconate (ccmuac) or adipate exchange. The aromatic upstream is modellable; the product is not.

Caveats (disclosed up front)

• FBA proves a route is stoichiometrically POSSIBLE, not that a living cell will do it.
• Every consortium here is a HYPOTHESIS until cultured; nothing is wet-lab validated.
• Feedstock-dependence is the anti-medium-artifact control: withdraw the feed and the product must collapse (a NOT-feedstock-dependent result is flagged SUSPECT, not a discovery).
• The ranking score is a documented heuristic for human review, not a truth or biology claim.
• Stage-1 selects finisher x diverse front-ends; multi-finisher relays are out of scope. Stage-2 expansion of winners is pending -- these are PRELIMINARY until it runs.